Transcript Detail IRES Map
Queried Transcript
| Transcript Info | Conservation | Conditional Translation Efficiency | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Accession | Genome Location |
Trascribed Gene |
5'UTR | CDS | Stop Codon | 3'UTR | Average Phastcon Score |
ER stressed | Normal |
ER/Normal Ratio |
| NM_001376 | chr14: + (location) |
DYNC1H1 |
119 bps (seq) |
13938 bps (seq) |
14058 ..14061 (TAA) |
5880 bps (seq) |
0.931 | 1.786 | 1.164 |
1.534 (q = 0.000E+0*) |
Identified Putative IRES Elements
* indicates statistical significance:
(Thresholds
selected on a ground truth dataset)
1. Conservation Score q-value < 1.000E-6
2. RPI Score q-value < 1.000E-6.
3. Ratio (difference) q-value < 1.000E-6.
| IRES Info | Conservation |
Conditional
Translation Efficiency |
Translation Initiation-related Info Summary for the IRES | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Putative IRES | Identifying Tools |
Average Phastcon Score (ref) |
ER Stressed | Normal | ER/Normal Ratio (ref) |
# of eTIS
(ref) |
# of nTIS
(ref) |
# of uORF
(ref) |
# of ITAF Binding Events (ref) |
RPI Significance |
IRES activity (ref) |
# of Literature Evidence |
|
IRES 1 20..119 (seq) (location) |
UTRscan |
0.069
(q = 1.000) |
3.004 | 1.124 |
2.673 (q = 4.254E-28*) |
0 | 0 | 0 | 4 | q = 7.604E-12* | -- | 0 |
IRES-Translation Initiation Interaction Map
(TIS refers to the main ORF initiating codon)
Detailed Translation Initiation-Related Data
Phastcon Conservation Scores (Among 19 Mammalian Species)
| Interconnected IRES |
Transcript Location |
Chromosomal Location |
Conservation Score |
|---|---|---|---|
| IRES 1 (20..119) | 20 | chr14 (+): 101964592 | 0.088 |
| IRES 1 (20..119) | 21 | chr14 (+): 101964593 | 0.017 |
| IRES 1 (20..119) | 22 | chr14 (+): 101964594 | 0.003 |
| IRES 1 (20..119) | 23 | chr14 (+): 101964595 | 0.000 |
| IRES 1 (20..119) | 24 | chr14 (+): 101964596 | 0.001 |
| IRES 1 (20..119) | 25 | chr14 (+): 101964597 | 0.000 |
| IRES 1 (20..119) | 26 | chr14 (+): 101964598 | 0.000 |
| IRES 1 (20..119) | 27 | chr14 (+): 101964599 | 0.000 |
| IRES 1 (20..119) | 28 | chr14 (+): 101964600 | 0.000 |
| IRES 1 (20..119) | 29 | chr14 (+): 101964601 | 0.000 |
| IRES 1 (20..119) | 30 | chr14 (+): 101964602 | 0.001 |
| IRES 1 (20..119) | 31 | chr14 (+): 101964603 | 0.003 |
| IRES 1 (20..119) | 32 | chr14 (+): 101964604 | 0.003 |
| IRES 1 (20..119) | 33 | chr14 (+): 101964605 | 0.004 |
| IRES 1 (20..119) | 34 | chr14 (+): 101964606 | 0.007 |
| IRES 1 (20..119) | 35 | chr14 (+): 101964607 | 0.022 |
| IRES 1 (20..119) | 36 | chr14 (+): 101964608 | 0.028 |
| IRES 1 (20..119) | 37 | chr14 (+): 101964609 | 0.040 |
| IRES 1 (20..119) | 38 | chr14 (+): 101964610 | 0.045 |
| IRES 1 (20..119) | 39 | chr14 (+): 101964611 | 0.044 |
| IRES 1 (20..119) | 40 | chr14 (+): 101964612 | 0.060 |
| IRES 1 (20..119) | 41 | chr14 (+): 101964613 | 0.067 |
| IRES 1 (20..119) | 42 | chr14 (+): 101964614 | 0.083 |
| IRES 1 (20..119) | 43 | chr14 (+): 101964615 | 0.088 |
| IRES 1 (20..119) | 44 | chr14 (+): 101964616 | 0.086 |
| IRES 1 (20..119) | 45 | chr14 (+): 101964617 | 0.075 |
| IRES 1 (20..119) | 46 | chr14 (+): 101964618 | 0.068 |
| IRES 1 (20..119) | 47 | chr14 (+): 101964619 | 0.053 |
| IRES 1 (20..119) | 48 | chr14 (+): 101964620 | 0.044 |
| IRES 1 (20..119) | 49 | chr14 (+): 101964621 | 0.039 |
| IRES 1 (20..119) | 50 | chr14 (+): 101964622 | 0.026 |
| IRES 1 (20..119) | 51 | chr14 (+): 101964623 | 0.000 |
| IRES 1 (20..119) | 52 | chr14 (+): 101964624 | 0.000 |
| IRES 1 (20..119) | 53 | chr14 (+): 101964625 | 0.000 |
| IRES 1 (20..119) | 54 | chr14 (+): 101964626 | 0.000 |
| IRES 1 (20..119) | 55 | chr14 (+): 101964627 | 0.001 |
| IRES 1 (20..119) | 56 | chr14 (+): 101964628 | 0.008 |
| IRES 1 (20..119) | 57 | chr14 (+): 101964629 | 0.011 |
| IRES 1 (20..119) | 58 | chr14 (+): 101964630 | 0.011 |
| IRES 1 (20..119) | 59 | chr14 (+): 101964631 | 0.012 |
| IRES 1 (20..119) | 60 | chr14 (+): 101964632 | 0.016 |
| IRES 1 (20..119) | 61 | chr14 (+): 101964633 | 0.016 |
| IRES 1 (20..119) | 62 | chr14 (+): 101964634 | 0.012 |
| IRES 1 (20..119) | 63 | chr14 (+): 101964635 | 0.011 |
| IRES 1 (20..119) | 64 | chr14 (+): 101964636 | 0.010 |
| IRES 1 (20..119) | 65 | chr14 (+): 101964637 | 0.007 |
| IRES 1 (20..119) | 66 | chr14 (+): 101964638 | 0.009 |
| IRES 1 (20..119) | 67 | chr14 (+): 101964639 | 0.013 |
| IRES 1 (20..119) | 68 | chr14 (+): 101964640 | 0.012 |
| IRES 1 (20..119) | 69 | chr14 (+): 101964641 | 0.008 |
| IRES 1 (20..119) | 70 | chr14 (+): 101964642 | 0.016 |
| IRES 1 (20..119) | 71 | chr14 (+): 101964643 | 0.028 |
| IRES 1 (20..119) | 72 | chr14 (+): 101964644 | 0.032 |
| IRES 1 (20..119) | 73 | chr14 (+): 101964645 | 0.015 |
| IRES 1 (20..119) | 74 | chr14 (+): 101964646 | 0.013 |
| IRES 1 (20..119) | 75 | chr14 (+): 101964647 | 0.012 |
| IRES 1 (20..119) | 76 | chr14 (+): 101964648 | 0.014 |
| IRES 1 (20..119) | 77 | chr14 (+): 101964649 | 0.017 |
| IRES 1 (20..119) | 78 | chr14 (+): 101964650 | 0.017 |
| IRES 1 (20..119) | 79 | chr14 (+): 101964651 | 0.015 |
| IRES 1 (20..119) | 80 | chr14 (+): 101964652 | 0.013 |
| IRES 1 (20..119) | 81 | chr14 (+): 101964653 | 0.009 |
| IRES 1 (20..119) | 82 | chr14 (+): 101964654 | 0.002 |
| IRES 1 (20..119) | 83 | chr14 (+): 101964655 | 0.001 |
| IRES 1 (20..119) | 84 | chr14 (+): 101964656 | 0.000 |
| IRES 1 (20..119) | 85 | chr14 (+): 101964657 | 0.000 |
| IRES 1 (20..119) | 86 | chr14 (+): 101964658 | 0.001 |
| IRES 1 (20..119) | 87 | chr14 (+): 101964659 | 0.001 |
| IRES 1 (20..119) | 88 | chr14 (+): 101964660 | 0.006 |
| IRES 1 (20..119) | 89 | chr14 (+): 101964661 | 0.010 |
| IRES 1 (20..119) | 90 | chr14 (+): 101964662 | 0.006 |
| IRES 1 (20..119) | 91 | chr14 (+): 101964663 | 0.006 |
| IRES 1 (20..119) | 92 | chr14 (+): 101964664 | 0.007 |
| IRES 1 (20..119) | 93 | chr14 (+): 101964665 | 0.010 |
| IRES 1 (20..119) | 94 | chr14 (+): 101964666 | 0.011 |
| IRES 1 (20..119) | 95 | chr14 (+): 101964667 | 0.008 |
| IRES 1 (20..119) | 96 | chr14 (+): 101964668 | 0.007 |
| IRES 1 (20..119) | 97 | chr14 (+): 101964669 | 0.003 |
| IRES 1 (20..119) | 98 | chr14 (+): 101964670 | 0.002 |
| IRES 1 (20..119) | 99 | chr14 (+): 101964671 | 0.003 |
| IRES 1 (20..119) | 100 | chr14 (+): 101964672 | 0.003 |
| IRES 1 (20..119) | 101 | chr14 (+): 101964673 | 0.004 |
| IRES 1 (20..119) | 102 | chr14 (+): 101964674 | 0.006 |
| IRES 1 (20..119) | 103 | chr14 (+): 101964675 | 0.010 |
| IRES 1 (20..119) | 104 | chr14 (+): 101964676 | 0.011 |
| IRES 1 (20..119) | 105 | chr14 (+): 101964677 | 0.014 |
| IRES 1 (20..119) | 106 | chr14 (+): 101964678 | 0.018 |
| IRES 1 (20..119) | 107 | chr14 (+): 101964679 | 0.020 |
| IRES 1 (20..119) | 108 | chr14 (+): 101964680 | 0.035 |
| IRES 1 (20..119) | 109 | chr14 (+): 101964681 | 0.062 |
| IRES 1 (20..119) | 110 | chr14 (+): 101964682 | 0.108 |
| IRES 1 (20..119) | 111 | chr14 (+): 101964683 | 0.188 |
| IRES 1 (20..119) | 112 | chr14 (+): 101964684 | 0.230 |
| IRES 1 (20..119) | 113 | chr14 (+): 101964685 | 0.296 |
| IRES 1 (20..119) | 114 | chr14 (+): 101964686 | 0.413 |
| IRES 1 (20..119) | 115 | chr14 (+): 101964687 | 0.466 |
| IRES 1 (20..119) | 116 | chr14 (+): 101964688 | 0.804 |
| IRES 1 (20..119) | 117 | chr14 (+): 101964689 | 0.850 |
| IRES 1 (20..119) | 118 | chr14 (+): 101964690 | 0.923 |
| IRES 1 (20..119) | 119 | chr14 (+): 101964691 | 0.962 |
Potential IRES Structural Form
IRES 1
(20.. 119)
Best Predicted IRES Structural Form:
..((((((((((..(((((.........((.....)).........)))))))))).))))).........(((((..(((...))).))))).......
Predicted by: MXSCARNA
Structural RPI Interpretability Significance: q = 7.604E-12*
(Visualization)
Conditional Translation Activity
ER-Stressed Ribisome Profiling (TM-treated)
| Interconnected IRES |
Transcript Location |
Chromosomal Location |
Stressed Translation Activity |
|---|---|---|---|
| IRES 1 (20..119) | 20 | chr14 (+): 101964592 | 0.234933799315 |
| IRES 1 (20..119) | 21 | chr14 (+): 101964593 | 0.234933799315 |
| IRES 1 (20..119) | 22 | chr14 (+): 101964594 | 0.234933799315 |
| IRES 1 (20..119) | 23 | chr14 (+): 101964595 | 0.234933799315 |
| IRES 1 (20..119) | 24 | chr14 (+): 101964596 | 0.234933799315 |
| IRES 1 (20..119) | 25 | chr14 (+): 101964597 | 0.234933799315 |
| IRES 1 (20..119) | 26 | chr14 (+): 101964598 | 0.234933799315 |
| IRES 1 (20..119) | 27 | chr14 (+): 101964599 | 0.234933799315 |
| IRES 1 (20..119) | 28 | chr14 (+): 101964600 | 0.234933799315 |
| IRES 1 (20..119) | 29 | chr14 (+): 101964601 | 0.0782979262632 |
| IRES 1 (20..119) | 30 | chr14 (+): 101964602 | 0.0782979262632 |
| IRES 1 (20..119) | 31 | chr14 (+): 101964603 | 0.0782979262632 |
| IRES 1 (20..119) | 32 | chr14 (+): 101964604 | 0.0782979262632 |
| IRES 1 (20..119) | 33 | chr14 (+): 101964605 | 0.0782979262632 |
| IRES 1 (20..119) | 34 | chr14 (+): 101964606 | 0.0782979262632 |
| IRES 1 (20..119) | 35 | chr14 (+): 101964607 | 0.0782979262632 |
| IRES 1 (20..119) | 36 | chr14 (+): 101964608 | 0.0782979262632 |
| IRES 1 (20..119) | 37 | chr14 (+): 101964609 | 0.0782979262632 |
| IRES 1 (20..119) | 38 | chr14 (+): 101964610 | 0.0782979262632 |
| IRES 1 (20..119) | 39 | chr14 (+): 101964611 | 0.0782979262632 |
| IRES 1 (20..119) | 40 | chr14 (+): 101964612 | 0.0782979262632 |
| IRES 1 (20..119) | 41 | chr14 (+): 101964613 | 0.0782979262632 |
| IRES 1 (20..119) | 42 | chr14 (+): 101964614 | 0.156615745312 |
| IRES 1 (20..119) | 43 | chr14 (+): 101964615 | 0.783160177337 |
| IRES 1 (20..119) | 44 | chr14 (+): 101964616 | 1.64467913407 |
| IRES 1 (20..119) | 45 | chr14 (+): 101964617 | 1.64467913407 |
| IRES 1 (20..119) | 46 | chr14 (+): 101964618 | 1.72299718807 |
| IRES 1 (20..119) | 47 | chr14 (+): 101964619 | 2.5061777281 |
| IRES 1 (20..119) | 48 | chr14 (+): 101964620 | 2.66281383611 |
| IRES 1 (20..119) | 49 | chr14 (+): 101964621 | 2.89776799812 |
| IRES 1 (20..119) | 50 | chr14 (+): 101964622 | 3.44599437614 |
| IRES 1 (20..119) | 51 | chr14 (+): 101964623 | 3.83758464615 |
| IRES 1 (20..119) | 52 | chr14 (+): 101964624 | 4.07253880816 |
| IRES 1 (20..119) | 53 | chr14 (+): 101964625 | 4.22917491617 |
| IRES 1 (20..119) | 54 | chr14 (+): 101964626 | 4.54244713218 |
| IRES 1 (20..119) | 55 | chr14 (+): 101964627 | 4.69908324019 |
| IRES 1 (20..119) | 56 | chr14 (+): 101964628 | 4.77740129419 |
| IRES 1 (20..119) | 57 | chr14 (+): 101964629 | 4.77740129419 |
| IRES 1 (20..119) | 58 | chr14 (+): 101964630 | 4.77740129419 |
| IRES 1 (20..119) | 59 | chr14 (+): 101964631 | 4.9340374022 |
| IRES 1 (20..119) | 60 | chr14 (+): 101964632 | 4.9340374022 |
| IRES 1 (20..119) | 61 | chr14 (+): 101964633 | 4.9340374022 |
| IRES 1 (20..119) | 62 | chr14 (+): 101964634 | 5.0123554562 |
| IRES 1 (20..119) | 63 | chr14 (+): 101964635 | 5.0123554562 |
| IRES 1 (20..119) | 64 | chr14 (+): 101964636 | 5.0906735102 |
| IRES 1 (20..119) | 65 | chr14 (+): 101964637 | 5.0906735102 |
| IRES 1 (20..119) | 66 | chr14 (+): 101964638 | 5.24730961821 |
| IRES 1 (20..119) | 67 | chr14 (+): 101964639 | 5.24730961821 |
| IRES 1 (20..119) | 68 | chr14 (+): 101964640 | 5.24730961821 |
| IRES 1 (20..119) | 69 | chr14 (+): 101964641 | 5.24730961821 |
| IRES 1 (20..119) | 70 | chr14 (+): 101964642 | 5.16899156421 |
| IRES 1 (20..119) | 71 | chr14 (+): 101964643 | 5.16899156421 |
| IRES 1 (20..119) | 72 | chr14 (+): 101964644 | 5.0906735102 |
| IRES 1 (20..119) | 73 | chr14 (+): 101964645 | 5.0906735102 |
| IRES 1 (20..119) | 74 | chr14 (+): 101964646 | 4.69908324019 |
| IRES 1 (20..119) | 75 | chr14 (+): 101964647 | 4.30749297017 |
| IRES 1 (20..119) | 76 | chr14 (+): 101964648 | 4.22917491617 |
| IRES 1 (20..119) | 77 | chr14 (+): 101964649 | 3.60263048414 |
| IRES 1 (20..119) | 78 | chr14 (+): 101964650 | 3.52431243014 |
| IRES 1 (20..119) | 79 | chr14 (+): 101964651 | 2.89776799812 |
| IRES 1 (20..119) | 80 | chr14 (+): 101964652 | 2.34954162009 |
| IRES 1 (20..119) | 81 | chr14 (+): 101964653 | 2.11458745808 |
| IRES 1 (20..119) | 82 | chr14 (+): 101964654 | 1.48804302606 |
| IRES 1 (20..119) | 83 | chr14 (+): 101964655 | 1.95795135008 |
| IRES 1 (20..119) | 84 | chr14 (+): 101964656 | 2.11458745808 |
| IRES 1 (20..119) | 85 | chr14 (+): 101964657 | 2.19290551209 |
| IRES 1 (20..119) | 86 | chr14 (+): 101964658 | 1.72299718807 |
| IRES 1 (20..119) | 87 | chr14 (+): 101964659 | 1.80131524207 |
| IRES 1 (20..119) | 88 | chr14 (+): 101964660 | 1.87963329607 |
| IRES 1 (20..119) | 89 | chr14 (+): 101964661 | 1.95795135008 |
| IRES 1 (20..119) | 90 | chr14 (+): 101964662 | 2.03626940408 |
| IRES 1 (20..119) | 91 | chr14 (+): 101964663 | 2.50614640088 |
| IRES 1 (20..119) | 92 | chr14 (+): 101964664 | 2.50614640088 |
| IRES 1 (20..119) | 93 | chr14 (+): 101964665 | 2.50614640088 |
| IRES 1 (20..119) | 94 | chr14 (+): 101964666 | 2.66278250888 |
| IRES 1 (20..119) | 95 | chr14 (+): 101964667 | 2.81941861689 |
| IRES 1 (20..119) | 96 | chr14 (+): 101964668 | 3.21100888691 |
| IRES 1 (20..119) | 97 | chr14 (+): 101964669 | 3.21100888691 |
| IRES 1 (20..119) | 98 | chr14 (+): 101964670 | 3.44596304892 |
| IRES 1 (20..119) | 99 | chr14 (+): 101964671 | 3.52428110292 |
| IRES 1 (20..119) | 100 | chr14 (+): 101964672 | 3.68091721092 |
| IRES 1 (20..119) | 101 | chr14 (+): 101964673 | 4.15082553494 |
| IRES 1 (20..119) | 102 | chr14 (+): 101964674 | 4.77736996697 |
| IRES 1 (20..119) | 103 | chr14 (+): 101964675 | 4.77736996697 |
| IRES 1 (20..119) | 104 | chr14 (+): 101964676 | 4.77736996697 |
| IRES 1 (20..119) | 105 | chr14 (+): 101964677 | 4.77736996697 |
| IRES 1 (20..119) | 106 | chr14 (+): 101964678 | 4.85568802097 |
| IRES 1 (20..119) | 107 | chr14 (+): 101964679 | 5.01232412898 |
| IRES 1 (20..119) | 108 | chr14 (+): 101964680 | 5.01232412898 |
| IRES 1 (20..119) | 109 | chr14 (+): 101964681 | 5.01232412898 |
| IRES 1 (20..119) | 110 | chr14 (+): 101964682 | 5.09064218298 |
| IRES 1 (20..119) | 111 | chr14 (+): 101964683 | 5.16896023698 |
| IRES 1 (20..119) | 112 | chr14 (+): 101964684 | 5.16896023698 |
| IRES 1 (20..119) | 113 | chr14 (+): 101964685 | 5.16896023698 |
| IRES 1 (20..119) | 114 | chr14 (+): 101964686 | 5.01232412898 |
| IRES 1 (20..119) | 115 | chr14 (+): 101964687 | 4.69905191297 |
| IRES 1 (20..119) | 116 | chr14 (+): 101964688 | 4.62073385896 |
| IRES 1 (20..119) | 117 | chr14 (+): 101964689 | 4.69905191297 |
| IRES 1 (20..119) | 118 | chr14 (+): 101964690 | 4.93402957039 |
| IRES 1 (20..119) | 119 | chr14 (+): 101964691 | 4.93402957039 |
Normal Ribisome Profiling (TM-untreaed)
| Interconnected IRES |
Transcript Location |
Chromosomal Location |
Normal Translation Activity |
|---|---|---|---|
| IRES 1 (20..119) | 20 | chr14 (+): 101964592 | 0.0714857089345 |
| IRES 1 (20..119) | 21 | chr14 (+): 101964593 | 0.0714857089345 |
| IRES 1 (20..119) | 22 | chr14 (+): 101964594 | 0.0714857089345 |
| IRES 1 (20..119) | 23 | chr14 (+): 101964595 | 0.0714857089345 |
| IRES 1 (20..119) | 24 | chr14 (+): 101964596 | 0.0714857089345 |
| IRES 1 (20..119) | 25 | chr14 (+): 101964597 | 0.0714857089345 |
| IRES 1 (20..119) | 26 | chr14 (+): 101964598 | 0.0714857089345 |
| IRES 1 (20..119) | 27 | chr14 (+): 101964599 | 0.0714857089345 |
| IRES 1 (20..119) | 28 | chr14 (+): 101964600 | 0.0714857089345 |
| IRES 1 (20..119) | 29 | chr14 (+): 101964601 | 0.0714857089345 |
| IRES 1 (20..119) | 30 | chr14 (+): 101964602 | 0.0357428544672 |
| IRES 1 (20..119) | 31 | chr14 (+): 101964603 | 0.0357428544672 |
| IRES 1 (20..119) | 32 | chr14 (+): 101964604 | 0.0357428544672 |
| IRES 1 (20..119) | 33 | chr14 (+): 101964605 | 0.0357428544672 |
| IRES 1 (20..119) | 34 | chr14 (+): 101964606 | 0.0357428544672 |
| IRES 1 (20..119) | 35 | chr14 (+): 101964607 | 0.0357428544672 |
| IRES 1 (20..119) | 36 | chr14 (+): 101964608 | 0.0357428544672 |
| IRES 1 (20..119) | 37 | chr14 (+): 101964609 | 0.0357428544672 |
| IRES 1 (20..119) | 38 | chr14 (+): 101964610 | 0.0357428544672 |
| IRES 1 (20..119) | 39 | chr14 (+): 101964611 | 0.0357428544672 |
| IRES 1 (20..119) | 40 | chr14 (+): 101964612 | 0.0357428544672 |
| IRES 1 (20..119) | 41 | chr14 (+): 101964613 | 0.0357428544672 |
| IRES 1 (20..119) | 42 | chr14 (+): 101964614 | 0.0357428544672 |
| IRES 1 (20..119) | 43 | chr14 (+): 101964615 | 0.39317139914 |
| IRES 1 (20..119) | 44 | chr14 (+): 101964616 | 0.679114234878 |
| IRES 1 (20..119) | 45 | chr14 (+): 101964617 | 0.714857089345 |
| IRES 1 (20..119) | 46 | chr14 (+): 101964618 | 0.893571361681 |
| IRES 1 (20..119) | 47 | chr14 (+): 101964619 | 1.14377134295 |
| IRES 1 (20..119) | 48 | chr14 (+): 101964620 | 1.17951419742 |
| IRES 1 (20..119) | 49 | chr14 (+): 101964621 | 1.28674276082 |
| IRES 1 (20..119) | 50 | chr14 (+): 101964622 | 1.39397132422 |
| IRES 1 (20..119) | 51 | chr14 (+): 101964623 | 1.50119988762 |
| IRES 1 (20..119) | 52 | chr14 (+): 101964624 | 1.60842845103 |
| IRES 1 (20..119) | 53 | chr14 (+): 101964625 | 1.64417130549 |
| IRES 1 (20..119) | 54 | chr14 (+): 101964626 | 1.71565701443 |
| IRES 1 (20..119) | 55 | chr14 (+): 101964627 | 1.71565701443 |
| IRES 1 (20..119) | 56 | chr14 (+): 101964628 | 1.7513998689 |
| IRES 1 (20..119) | 57 | chr14 (+): 101964629 | 1.7513998689 |
| IRES 1 (20..119) | 58 | chr14 (+): 101964630 | 1.7513998689 |
| IRES 1 (20..119) | 59 | chr14 (+): 101964631 | 1.7513998689 |
| IRES 1 (20..119) | 60 | chr14 (+): 101964632 | 1.7513998689 |
| IRES 1 (20..119) | 61 | chr14 (+): 101964633 | 1.78714272336 |
| IRES 1 (20..119) | 62 | chr14 (+): 101964634 | 1.78714272336 |
| IRES 1 (20..119) | 63 | chr14 (+): 101964635 | 1.78714272336 |
| IRES 1 (20..119) | 64 | chr14 (+): 101964636 | 1.78714272336 |
| IRES 1 (20..119) | 65 | chr14 (+): 101964637 | 1.82288557783 |
| IRES 1 (20..119) | 66 | chr14 (+): 101964638 | 1.8586284323 |
| IRES 1 (20..119) | 67 | chr14 (+): 101964639 | 1.8586284323 |
| IRES 1 (20..119) | 68 | chr14 (+): 101964640 | 1.89437128676 |
| IRES 1 (20..119) | 69 | chr14 (+): 101964641 | 1.89437128676 |
| IRES 1 (20..119) | 70 | chr14 (+): 101964642 | 1.89437128676 |
| IRES 1 (20..119) | 71 | chr14 (+): 101964643 | 1.89437128676 |
| IRES 1 (20..119) | 72 | chr14 (+): 101964644 | 1.8586284323 |
| IRES 1 (20..119) | 73 | chr14 (+): 101964645 | 1.82288557783 |
| IRES 1 (20..119) | 74 | chr14 (+): 101964646 | 1.57268559656 |
| IRES 1 (20..119) | 75 | chr14 (+): 101964647 | 1.28674276082 |
| IRES 1 (20..119) | 76 | chr14 (+): 101964648 | 1.21898503161 |
| IRES 1 (20..119) | 77 | chr14 (+): 101964649 | 1.11175646821 |
| IRES 1 (20..119) | 78 | chr14 (+): 101964650 | 1.04027075927 |
| IRES 1 (20..119) | 79 | chr14 (+): 101964651 | 0.897299341402 |
| IRES 1 (20..119) | 80 | chr14 (+): 101964652 | 0.53987079673 |
| IRES 1 (20..119) | 81 | chr14 (+): 101964653 | 0.53987079673 |
| IRES 1 (20..119) | 82 | chr14 (+): 101964654 | 0.361156524393 |
| IRES 1 (20..119) | 83 | chr14 (+): 101964655 | 0.432642233328 |
| IRES 1 (20..119) | 84 | chr14 (+): 101964656 | 0.754327923533 |
| IRES 1 (20..119) | 85 | chr14 (+): 101964657 | 0.790070778 |
| IRES 1 (20..119) | 86 | chr14 (+): 101964658 | 0.754327923533 |
| IRES 1 (20..119) | 87 | chr14 (+): 101964659 | 0.754327923533 |
| IRES 1 (20..119) | 88 | chr14 (+): 101964660 | 0.754327923533 |
| IRES 1 (20..119) | 89 | chr14 (+): 101964661 | 0.754327923533 |
| IRES 1 (20..119) | 90 | chr14 (+): 101964662 | 0.790070778 |
| IRES 1 (20..119) | 91 | chr14 (+): 101964663 | 0.897299341402 |
| IRES 1 (20..119) | 92 | chr14 (+): 101964664 | 1.0045279048 |
| IRES 1 (20..119) | 93 | chr14 (+): 101964665 | 1.07601361374 |
| IRES 1 (20..119) | 94 | chr14 (+): 101964666 | 1.14749932267 |
| IRES 1 (20..119) | 95 | chr14 (+): 101964667 | 1.11175646821 |
| IRES 1 (20..119) | 96 | chr14 (+): 101964668 | 1.14749932267 |
| IRES 1 (20..119) | 97 | chr14 (+): 101964669 | 1.21898503161 |
| IRES 1 (20..119) | 98 | chr14 (+): 101964670 | 1.29047074054 |
| IRES 1 (20..119) | 99 | chr14 (+): 101964671 | 1.29047074054 |
| IRES 1 (20..119) | 100 | chr14 (+): 101964672 | 1.57641357628 |
| IRES 1 (20..119) | 101 | chr14 (+): 101964673 | 1.68364213968 |
| IRES 1 (20..119) | 102 | chr14 (+): 101964674 | 1.89809926649 |
| IRES 1 (20..119) | 103 | chr14 (+): 101964675 | 1.93011414123 |
| IRES 1 (20..119) | 104 | chr14 (+): 101964676 | 1.89437128676 |
| IRES 1 (20..119) | 105 | chr14 (+): 101964677 | 1.93011414123 |
| IRES 1 (20..119) | 106 | chr14 (+): 101964678 | 1.93011414123 |
| IRES 1 (20..119) | 107 | chr14 (+): 101964679 | 2.00159985017 |
| IRES 1 (20..119) | 108 | chr14 (+): 101964680 | 2.00159985017 |
| IRES 1 (20..119) | 109 | chr14 (+): 101964681 | 2.00159985017 |
| IRES 1 (20..119) | 110 | chr14 (+): 101964682 | 2.00159985017 |
| IRES 1 (20..119) | 111 | chr14 (+): 101964683 | 2.0730855591 |
| IRES 1 (20..119) | 112 | chr14 (+): 101964684 | 2.10882841357 |
| IRES 1 (20..119) | 113 | chr14 (+): 101964685 | 2.0730855591 |
| IRES 1 (20..119) | 114 | chr14 (+): 101964686 | 1.89437128676 |
| IRES 1 (20..119) | 115 | chr14 (+): 101964687 | 1.7513998689 |
| IRES 1 (20..119) | 116 | chr14 (+): 101964688 | 1.7513998689 |
| IRES 1 (20..119) | 117 | chr14 (+): 101964689 | 1.71565701443 |
| IRES 1 (20..119) | 118 | chr14 (+): 101964690 | 1.93011414123 |
| IRES 1 (20..119) | 119 | chr14 (+): 101964691 | 1.9658569957 |
Experimentally-Probed TIS (eTIS)
| Interconnected IRES | TIS Transcript Location |
TIS Chromosomal Location |
Codon |
|---|
Predicted Non-canonical TIS (nTIS)
| Interconnected IRES | TIS Transcript Location |
TIS Chromosomal Location |
Non-canonical Start Codon |
Confidence |
|---|
uORF
| Interconnected IRES |
uORF Transcript Location |
uORF Chromosomal Location |
uORF Sequence | Sequence |
|---|
ITAF Binding Events
| Interconnected IRES |
ITAF Type | ITAF Transcript Location |
ITAF Chromosomal Location |
ITAF Sequence |
Sequence | Identified Score |
|---|---|---|---|---|---|---|
| IRES 1 (20..119) | HuR/ELAVL1 w/ MNase (PAR-CLIP, HEK293 cells, Kishore 2011) | 8..48 |
chr14 (+) : 101964580 - 101964620. |
41 bps (seq) | GGUGGGCUAGCGGACGGUCCGGCUUCCGGCGGCCGUUUCUG | 2 |
| IRES 1 (20..119) | eIF4A3 (HITS CLIP, Hela cells replicate 1) | 15..375 |
chr14 (+) : 101964587 - 101964947. |
361 bps (seq) | UAGCGGACGGUCCGGCUUCCGGCGGCCGUUUCUGUCUCUUGCUGGCUGUCUCGCUGAGUCGCGGCCGCCUUCUCAUCGCUCCUGGAAGGUCCCGAGCGCGACACCAUGUCGGAGCCCGGGGGCGGCGGCGGCGAGGACGGCUCGGCCGGAUUGGAAGUGUCGGCCGUGCAGAAUGUGGCGGACGUGUCGGUGCUGCAGAAGCACCUGCGCAAGCUGGUGCCGCUGCUGCUGGAGGACGGCGGCGAGGCGCCGGCCGCGCUGGAGGCGGCGCUGGAGGAGAAGAGCGCCCUGGAGCAGAUGCGCAAGUUCCUUUCGGACCCGCAGGUCCACACGGUGCUGGUGGAGCGCUCCACGCUCAAAG | 57 |
| IRES 1 (20..119) | FUS (HITS CLIP, brain cells replicate 2) | 70..92 |
chr14 (+) : 101964642 - 101964664. |
23 bps (seq) | GAGUCGCGGCCGCCUUCUCAUCG | 1 |
| IRES 1 (20..119) | eIF4A3 (HITS CLIP, Hela cells replicate 2) | 117..212 |
chr14 (+) : 101964689 - 101964784. |
96 bps (seq) | ACCAUGUCGGAGCCCGGGGGCGGCGGCGGCGAGGACGGCUCGGCCGGAUUGGAAGUGUCGGCCGUGCAGAAUGUGGCGGACGUGUCGGUGCUGCAG | 5 |
IRES Activity Measurements
| Interconnected IRES |
IRES Activity |
Promoter Activity |
Splicing Activity |
Matched Transcript Location |
Matched Transcript Sequence | Matched Chromosomal Location |
Designed Human Oligo Sequence |
Designed Oligo Sequence | BLASTN Query Cover |
BLASTN Percent Identity |
|---|
IRES Elements Verified in the Literature
| Interconnected IRES |
Matched Transcript Location |
Matched Transcript Sequence | Matched Chromosomal Location |
Literature Verified Sequence |
Verified Sequence | BLASTN Query Cover |
BLASTN Percent Identity |
Reference |
|---|
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